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Arch Biochem Biophys, 2016

"TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth"

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Pilose antler peptide-3.2KD (PAP-3.2KD) has multiple biological activities in cardiomyopathy and reverses histological changes in cardiac tissue by decreasing TGF-1, Smad2/3/4, and P-Smad2/3 levels, elevating Smad7 protein levels, thereby regulating pathological changes in the TGF-/Smad signaling pathway, such as myofascial disorders, MF, and diffuse CMs edema (75)

Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis