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Although, the composition and position (i.e., intra- or extracellular) of protein aggregates are different from disease to disease, this common characteristic shows that protein deposition per se , or some related event, is toxic to neurons (Dauer and Przedborski, The pathological changes of PD are characterized by degeneration of DA neurons in the substantia nigra and formation of Lewy body (LB) in neurons (Scherfler et al., 2007)

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[DOI] [PubMed] 506.Xi J, Zhang Z, Wang Z, Wu Q, He Y, Xu Y, et al

These triggers commonly disrupt the mitochondrial membrane potential (m) and electron transport chain integrity

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The Zen Cocktail combines glutathione with NAD+ and amino acids for broader cellular support