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Int J Biol Macromol 186:800810
The reasons for these discrepancies are unclear although a follow-up study from Erickson et al attributed the discrepant results to a lack of functional consequence in the ARE mutant used by Galloway and McLellan (Erickson et al., 2002)

Specifically, LO2 hepatocytes were engineered to overexpress CD47-HuR (designated as LO2 CD47 HuR ), and exosomes were harvested via centrifugation from these cells (termed Exos CD47HuR ) using the functionalized fusion protein

We did not observe any significant HFD-induced changes in GSSG levels or in the GSH:GSSG ratio

Muku GE, Murray IA, Perdew GH

2015;131:e29e39
