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Caveolin-1 directly binds cholesterol and long-chain free fatty acids facilitating their transport inside the cell and upregulates the expression of FAT/CD36 on the plasma membrane [18]

Less common but significant side effects observed in trials consist of altered skin sensation, severe dermal reactions, and increased susceptibility to allergic reactions

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In overweight cats, it has been associated with enhanced metabolic rate and increased fatty acid oxidation (Center SA, 2012)

Low response is due in part to over-representation in patients following liver transplantation of predictors of nonresponse, predictors such as genotype 1 and high viral load

8Des polyols (glycrol, sorbitol ou mannitol), des disaccharides (lactose) ou des sels (NaCl, MgSO 4 ) sont principalement utiliss afin de stabiliser les enzymes commercialises sous la forme d'une solution liquide concentre (Kristjansson et al., 1991)