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It facilitated phosphorylation of eNOS at Ser1177, leading to increased NO production, primarily through estrogen receptor-mediated PI3K/Akt signaling
J Biol Chem 272 : 2766027664 Shaw RJ and Cantley LC (2006) Ras, PI(3)K and mTOR signalling controls tumour cell growth
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[1] A significant increase in resting levels of blood nitrate/nitrite was noted for subjects receiving GPLC compared to placebo (in a double blind design)
Br J Clin Pharmacol 1998;46:101-110
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