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Diabetes 2009;58:773795 [DOI] [PMC free article] [PubMed] [Google Scholar] 3.Elrick H, Stimmler L, Hlad CJ Jr, Arai Y

The importance of the nine-amino acid C-terminal sequence of exendin-4 for binding to the GLP-1 receptor and for biological activity

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By targeting these, retatrutide may help suppress appetite and increase the bodys energy burn