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The mitochondrial toxins rotenone and 1-methy-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), two PD-associated inhibitors of mitochondrial complex I, can induce PD-like phenotypes both in vitro and in vivo [13]

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Cooper AA, Gitler AD, Cashikar A, Haynes CM, Hill KJ, Bhullar B et al (2006) Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinsons models

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