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Ann N Y Acad Sci 1043:553561
To reduce costs, many studies use solvents such as anhydrous acetic acid, propionic acid, and ethyl acetate
Available evidence suggests that these agents have similar efficacy, for example: An RCT comparing valproic acid and lacosamide found that the agents were equally efficacious when adequately dosed (e.g., 400 mg IV lacosamide)
Oxidative stress induced by methamphetamine in brain endothelial cells can cause impaired blood-brain barrier function
