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pH Effects Substrates PH not only affects the activity of the enzyme, but also affects the charge and shape of the substrate, so that the substrate cannot bind to the active site, or cannot be catalyzed to form a product

This makes it essential to maintain a sterile and safe environment for various medical procedures

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middlemen buy this unregulated powder in bulk, reconstitute it into vials, and sell them online for $40-$80, slapping a "Research Use Only" or "Not For Human Use" label on the side as a legal fig leaf

The consequences for positive tests include: Disqualification from competition Loss of medals and records Suspension from sport (potentially years) Stripped sponsorships and endorsements Permanent career damage Trace amounts -- even levels far below what would provide any performance benefit -- can still trigger positive tests and sanctions