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This Review explores the concept of metabotherapy, harnessing metabolites to prevent and treat gastrointestinal disorders, providing insights into metabolite classifications and their pathophysiological mechanisms in health and disease and mapping their potential as therapeutic targets.

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L-carnitine is also found in many animal-derived foods, such as red meat, fish, and dairy products

In irradiated mouse models, EGCGZn suppositories reduced oxidative stress, DNA damage, and inflammatory responses in rectal tissue, and promoted epithelial regeneration and tight junction restoration

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