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[DOI] [PubMed] [Google Scholar] 10.Zivanovic-Posilovic G., Balenovic D., Barisic I., Strinic D., Stambolija V., Udovicic M., Uzun S., Drmic D., Vlainic J., Bencic M.L., et al

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Safe S, Jayaraman A, Chapkin RS et al (2021) Flavonoids: structurefunction and mechanisms of action and opportunities for drug development

We also demonstrate the utility of HRMS discovery-based approach (sometimes referred to as pharmacometabolomics in clinical applications ( 35, 36 )) to advance a step forward towards precision and personalized medicine and uncover new metabolites markers that can be used to provide better typing of patients related to the kinetic of elimination of a drug or to identify inter-individual susceptibility to develop drug-induced liver injury, as it is the case here with APAP

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Re-sequencing of loci encoding putative proteases with the KLIKK ending PCR was performed using a CFX96 Touch machine (Bio-Rad Life Science Research, Hercules, CA)