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on acetaminophen-induced acute liver injury in mice
doi: 10.1002/ptr.8313 115 Lagunas-RangelFALiepinshEFredrikssonRAlsehliAMWilliamsMJDambrovaMet al

Such changes are consistent with the known roles of selenoproteins and highlight that changes in Se intake can affect the pathways that determine cell responses to oxidative and ER stress as well as the immune response

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Interestingly, Chac1 expression is decreased in livers of patients with MASLD, highlighting its potential therapeutic relevance
