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In imiquimod-induced lupus mice, the prebiotic Hirsutella sinensis polysaccharides and the probiotic Parabacteroides goldsteinii significantly reduced disease markers, including spleen weight, proteinuria, anti-dsDNA autoantibodies, and STAT signaling levels, while improving renal and hepatic function parameters

The synthesis of Chitosan@DOTAGA is performed using chitosan extracted from Alaska snow crabs with a weight-average molar mass (M w ) of 2.583 10 5 g mol 1 and a number-average molar mass (M n ) of 1.323 10 5 g mol 1

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10.1136/bmjopen-2021-053772 38 KumarH.HaD

Palinski W, Rosenfeld ME, Yla-Herttuala S, Gurtner GC, Socher SS, Butler SW, Parthasarathy S, Carew TE, Steinberg D, Witztum JL

Free Rad Res 39:573580 Zeevalk GD, Manzino L, Sonsalla PK, Bernard LP (2007) Characterization of intracellular elevation of glutathione (GSH) with glutathione monoethyl ester and GSH in brain and neuronal cultures: relevance to Parkinsons disease