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doi: 10.1080/00071668.2012.747084 245 OsorioJ

In addition, apart from the hydrolytic enzyme system, the redox enzyme systems within lysosomes in cells (such as NQO1, GSH, etc.) can also be used for the design of degradable linkers

Signaling impairments within the glutamatergic and cholinergic systems are the main targets of currently approved AD therapies (Parsons et al., 2013)

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Nutritional interventions play a pivotal role: consuming choline-rich foods, antioxidants, and lean proteins supports liver repair and muscle regeneration

Research approaches range from basic methods like bioassays and enzyme activity studies to advanced methodologies such as transcriptomics, proteomics, and functional gene analyses, all aimed at elucidating the molecular basis of pesticide detoxification