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With the Warburg effect, he described the metabolic shift in cancer cells from oxidative phosphorylation to an increased rate of aerobic glycolysis, to produce significantly higher amounts of ATP [46]

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linked NOTCH1 overexpression to reduced overall survival in GBM patients [31]

In conclusion, the close relationship between GM and H 2 should not be ignored, and the modulation of GM composition and function by H 2 and the modulation of GM metabolites by H 2 require indepth study, which will help to discover new therapeutic targets and mechanisms of action of H 2

Apart from vaccines and antiviral drugs, antiviral peptides (AVPs) have demonstrated preventive benefits against coronaviruses [16]