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Following this, 5 ml of 40% dextran solution were added to the rest of the homogenate before being centrifuged at 6000 RCF and 4C for 15 min using a fixed angle rotor

This essential nutrient helps protect skin from oxidative damage, supports wound healing, and contributes to a more radiant, even complexion

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found that TMAO can inhibit the RCT process and affect cholesterol metabolism ( ApoE / mice, and further activate the nuclear receptors farnesoid-X-receptor (FXR) and small heterodimer partner (SHP), to reduce the expression of cholesterol 7-hydroxylase (Cyp7a1) to inhibit bile acid synthesis, thus accelerating the formation of atherosclerosis ( coprostanol (a bacterial metabolite of cholesterol) ( Figure 3 Potential Therapeutic Measures of TMAO for AS Reduced Production of TMAO to Protect the Heart TMAO is an intestinal microbiota-dependent metabolite, which is accumulated in the body by ingestion of large amounts of substances rich in phosphatidylcholine