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These studies suggest that orally administered glutathione is absorbed into the blood and might have effects on the redox status in the human body

There is little data about the concentrations of GSH in the nucleus and endoplasmic reticulum largely because of a lack of adequate techniques to accurately determine the GSH pool at those locations (15, 69, 72, 73)

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doi: 10.1111/j.1432-1033.1988.tb14305.x