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Further evidence supporting the potential in situ deleterious effects of APAP in brain comes from studies showing that APAP increases neuronal CYP2E1 enzymatic activity and protein levels, leading to neuronal cell death through mitochondrial-mediated mechanisms that involve cytochrome c release and caspase 3 activation (130)

Argils JM

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As mentioned above, a normal microbiota regulates various aspects of epithelial barrier function, such as TJ expression, angiogenesis, vascular permeability and immunomodulation [2, 37]

A single-cell map of peripheral alterations after FMT treatment in patients with systemic lupus erythematosus