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Stratification ensures that the proportion of toxic and non-toxic classes is approximately the same in the full dataset and both splits

148 In addition to instigating the XBP1s-mediated transcriptional response, activated IRE1 also serves as a scaffolding protein that facilitates the activation of other signaling pathways

doi: 10.1016/j.nutres.2010.08.008 107 RaoCVDesaiDSimiBKulkarniNAminSReddyBS

While some studies found a positive association between higher Mn intake and an increased risk of metabolic syndromes, others reported the opposite effect, with some studies even suggesting gender-specific differences (Li and Yang, 2018)

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