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When administered as a once-weekly subcutaneous injection, Ozempic helps to: Stimulate insulin secretion from pancreatic beta cells in a glucose-dependent manner Suppress glucagon release , reducing hepatic glucose production Slow gastric emptying , which helps control post-meal blood sugar spikes Promote satiety , leading to reduced calorie intake and potential weight loss Ozempic treatment typically begins with a 0.25 mg weekly dose for 4 weeks, which is then increased to 0.5 mg weekly, with further titration to 1 mg if needed for glycaemic control

Thermogenesis , glucagon receptor stimulation increases resting energy expenditure in preclinical and clinical models

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Injection site reactions showed up in approximately 14 percent of participants at the highest dose tested