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3.4 Therapy-induced adaptations of oxphos via glucose metabolism Traditionally, glucose metabolism in the context of cancer has been focused on the canonical Warburg Effect, which postulates that cancer cells preferentially utilize glucose for the production of lactate during aerobic glycolysis, thus generating energy quickly even in cells with defective mitochondria (Warburg, 1925)

Uzun, N., Sarikaya, S., Uluduz, D., and Aydin, A

Similarly, budesonide conjugated with longer chain length esters (C16) improved local tolerability compared with shorter chain lengths

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