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Glucagonlike peptide 1 excites hypocretin/orexin neurons by direct and indirect mechanisms: Implications for visceramediated arousal

Focus on whole foods: vegetables, lean protein, legumes, whole grains in sensible portions, and healthy fats such as olive oil and nuts

Infection risks Using expired or improperly stored semaglutide from a multi-dose vial may increase the risk of infection

For example, a relatively high level of GLP-1R-immunoreactivity was observed in mouse hippocampus (Jensen et al., 2018) while a low level of GLP-1R-immunoreactivity was revealed in rat hippocampus (Farkas et al., 2021), which may suggest some species difference of the GLP-1R expression in the hippocampus

[1] Psyllium also slows gastric emptying on its own, which extends the GLP-1 response to a meal independent of fermentation

Or does it reflect a fundamentally different baseline of health