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At each review, clinicians should assess: Weight loss progress : Saxenda should be discontinued if patients have not lost at least 5% of initial body weight after 12 weeks at the maximum tolerated dose, as per NICE TA664 Tolerability and adherence : Address gastrointestinal side effects and ensure proper injection technique Cardiovascular risk factors : Monitor blood pressure and consider repeating lipid profiles at 3-6 months Safety concerns : Specifically enquire about abdominal pain, changes in bowel habit, or other concerning symptoms For patients with hypertriglyceridaemia, lipid profile monitoring should be performed at 3-6 months after starting Saxenda, then annually or as clinically indicated

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