does semaglutide cause swelling Ozempic Side Effects: Risks of This Injection Common And Rare Side Effects

Its unique mechanism of action, combining GLP-1, GIP and glucagon receptor agonism, has shown impressive weight loss and glycemic control in early phase clinical trials

[DOI] [PMC free article] [PubMed] [Google Scholar] 142.Heymann W.R

July 15, 2026

Hydration, eating smaller meals, and avoiding high-fat foods speed up this adjustment by reducing the workload on your digestive system while it acclimates

Personalization remains essential

With GLP-1 therapy Diet & exercise alone No intervention At 3 months ~5% average body weight loss* At 6 months ~10% average body weight loss* At 1 year ~15% average body weight loss* *Based on STEP 1 clinical trial data (semaglutide 2.4mg + lifestyle intervention)