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doi:10.1186/s12863-014-0152-1

This release of bile acids, mainly cholic (CA) and chenodeoxycholic (CDCA) acid derivatives, happens through the relaxation of the smooth muscle sphincter upon CCK signaling (336) or indirectly through a similar VIP action on the sphincter of Oddi (337)

The risk appeared class-wide, suggesting a mechanism related to GLP-1 receptor activity itself rather than formulation-specific differences
Clinical eligibility does not translate to real-world access
