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The findings are then validated through human interventions studies

Guanosine (GUO, an endogenous nucleoside) shows modulating functions of glutamate release, exerting a neuroprotective effect

While side effects can occur, they're typically mild and temporary

The free radicals are electrons with unpaired electrons, atoms or ions, which are chemically active and have extremely high oxidizing properties to capture the electron from nucleic acids, amino acids and other biomolecules, then led them turn into more toxic hydroxyl radicals, which can cause a variety of diseases in the body

Treatments targeting ERS or microcirculation disorders can also prevent AIH to some extent, but the protective mechanisms need to be further clarified in future clinical studies

doi: 10.1152/ajplung.00528.2005 43 ChallapalliACarrollLAboagyeEO