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Clinical Takeaways As the prevalence of obesity, insulin resistance, metabolic syndrome and associated health complications continue to rise, targeting GLP-1 activity has emerged as a promising strategy in improving cardiometabolic health and encouraging sustainable weight loss

These benefits are thought to result from improved blood glucose control, weight reduction, blood pressure lowering, and anti-inflammatory effects

The cAMP accumulation was measured using a cAMP Gs Dynamic Kit (Cisbio) and EnVision reader (PerkinElmer)