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doi: 10.3760/cma.j.cn115791-20220921-00485 70 TangT.SongJ.LiJ.WangH.ZhangY.SuoH

Atomic-resolution structure of the cellulose synthase regulator cyclic diguanylic acid

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Arab Universities J Agricultural Sci

MSNs have been designed to overcome it through various approaches: (i) surface modification with BBB-penetrating ligands (transferrin, angiopep-2), (ii) use of receptor-mediated transcytosis, (iii) nasal delivery for nose-to-brain targeting, and (iv) temporary BBB modulation (e.g., targeted ultrasound) in combination with MSN delivery [258,259]