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Background Renin-angiotensin system inhibitors (RASi) and sodium glucose cotransporter inhibitors (SGLT2i) are known for their kidney protective properties, but both show significant residual risk in large outcome trials

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Retatrutide vs Tirzepatide represents an important comparison for anyone looking at newer weight loss medications

AN is obesity's metabolic bookend. That connection explains why GLP-1 agonists carry serious risks for those predisposed to AN and with at least one in eight American adults now taking these drugs, the stakes couldn't be higher