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Instead, weight loss patches contain a varied range of ingredients from patch to patch

As a key trial evaluating the efficacy of tirzepatide, SURMOUNT-1 (NCT04184622) was consistent with the SURPASS studies in demonstrating dose-dependent weight loss [66]

It is categorised scientifically as a triple hormone receptor agonist, meaning it is synthesised to target three specific metabolic receptors simultaneously: GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide), and glucagon receptors

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However, GLP-1RAs also modestly reduce systolic blood pressure (SBP) by 24 mmHg (66)

Individual results vary based on starting BMI, genetic factors, lifestyle adherence, and dose escalation