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Moreover, human studies remain limited and heterogeneous, emphasizing the need for well-powered, placebo-controlled trials that assess both efficacy and safety across diverse populations and addiction types

Active Pancreatitis and Inflammatory Bowel Conditions Patients with a current diagnosis of acute pancreatitis should not initiate semaglutide therapy until inflammation resolves completely and pancreatic function normalizes

Cureus 16 , e52670 (2024)

Mounjaro may be discussed when: Tirzepatide is clinically appropriate

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