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Concurrently, the GIP component acts directly on adipose tissue to optimize lipid metabolism, while enhancing pancreatic insulin secretion in a glucose-dependent manner

While Mounjaro (tirzepatide) was originally approved for Type 2 diabetes, Zepbound (tirzepatide) is FDA-approved specifically for chronic weight management in adults with obesity (BMI 30 or above) or overweight (BMI 27 or above) with at least one weight-related condition such as hypertension, high cholesterol, or sleep apnea

Rosenstock, J., et al

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For every 10 degrees Celsius increase in storage temperature, the rate of peptide degradation roughly doubles