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In the early years of this research, Mojsov was the only researcher in a position to synthesize the needed peptides (see [32])

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The transcriptional upregulation of Ppara and Ppargc1a observed here reflects glucagon-driven mitochondrial activation [49], while the downregulation of lipogenic genes ( Fasn , Scd2 ) may stem from GIP receptor activation in adipocytes, redirecting nutrient flux away from storage