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p62 was the only gene to consistently show dose-dependent changes in expression for all drugs tested and at different concentrations (Figure 4a and Supplementary Figure 4)
Detailed experimental parameters, controls, and PAINS, risk assessments for each compound are provided in Supplementary Table S1
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The ability to maintain or restore optimal glutathione status represents a fundamental strategy for promoting healthspan and preventing oxidative stress-related pathological processes
