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Description
Future trials should include stage-stratified enrollment
The intracellular [Ca 2+ ] rise triggered by glycine (monitored as the 340/380 nm fluorescence ratio in fura-2-loaded cells) was inhibited by both strychnine (10 m) and picrotoxin (100 m), whereas the response to GABA was abolished by picrotoxin but only marginally impaired by strychnine (Fig
Other pharmaceutical companies are pursuing their own small-molecule approaches
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