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Diabetes Care 33:730732 Migoya EM, Bergeron R, Miller JL et al (2010) Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1

This is supported by recent evidence demonstrating that metabolic disorders such as type 2 diabetes (15, 52) and diet-induced obesity (30) are associated with downregulation in cilia genes known to be involved in proliferation, cell cycle control, and cilia motility (1) representing a potentially underexplored mechanism contributing to common obesity

The potential regulation of gluconeogenesis via HDAC and the robust induction of insulin secretion via GLP-1 appoint butyrate administration as a potential target for research in diabetes treatment

doi: 10.1007/s12630-020-01867-2

Incidence of headache with GLP-1 receptor agonists

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