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Tirzepatide, a dual agonist of Glucose-Dependent Insulinotropic Polypeptide (GIP) and Glucagon-Like Peptide 1 (GLP-1) receptors, improved glucose control and...

Incretin mimetics considerably expanded their proven benefits beyond obesity in 2024

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Additionally, GLP-1 analogs reduced energy expenditure, with only tirzepatide showing a significant decrease in the respiratory quotient (RQ) in MC4R KO mice

Preclinical and observational data suggested possible benefits, spurring rigorous clinical testing
