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Past month smokeless tobacco use among people aged 12 or older, by gender: 2002 to 2014 Figure 3

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Most pharmacology research is on tobacco and nicotine generally rather than rap specifically, and rap is a traditional preparation, not an approved medicine

Electronic smoking devices produce an aerosol of undetermined and potentially harmful substances

A warm and fast-draining location is preferred

By following approaches applied in previous research 12 , we considered low risk of bias if the total score was 1320, moderate risk of bias if the score was 712, and high risk of bias if the score was 6