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This pathological environment induces ferroptosis in fibroblasts, periodontal ligament cells, osteocytes, and immune cells such as macrophages, T cells, and neutrophils, contributing to tissue degradation and increased inflammation [12,13,14]

Storage: 20C recommended

The gradient started at 5% B (held for 2.5 min) and was linearly increased to 30% B within 37.5 min, to 50% B within 10 min, then to 85% B within 5 min (held for 3 min)

Additionally, lifestyle changes such as diet and exercise can reduce IL-6 levels, presenting non-pharmacological options for managing diabetes-related inflammation [15]

In total, 2400 participants were given vitamin C (1000 mg) and vitamin E (400 IU) or the placebo from the moment of recruitment until delivery