pfizer glp 1 oral Pfizer's Appetite for More Obesity Meds Leads to $150M Deal for GLP-1 Drug From China Danuglipron: An Oral GLP-1R Agonist
Description
Appetite suppression GLP-1 analogs act on the hypothalamus and brainstem to reduce hunger and increase satiety

45 The systemic distribution of GLP-1Rs underpins the diverse actions of GLP-1RAs beyond glycemic control and weight loss (Figure 1B)

Deep venous thrombosis (TVP): clots that are usually formed on the legs
A comprehensive meta-analysis published in 2017 examining data from over 60,000 patients found no significant increase in pancreatic cancer risk associated with GLP-1 receptor agonist use

Patients who shouldnt use compounded GLP-1 therapy include those who have a family history of specific cancers, including medullary thyroid cancer, or who have a rare disorder called multiple endocrine neoplasia type 2 syndrome

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