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doi: 10.1038/s41582-019-0157-5

Furthermore, given the aforementioned purported mechanisms for the improving effects of L-carnitine/synbiotics on weight or metabolic parameters, it could be conceived that concomitant supplementation of L-carnitine and synbiotics may confer more pronounced impacts on these indicators, potentially through simultaneous modulation of energy homeostasis (8, 30), increasing fatty acid oxidation (8, 30), reducing adipogenesis or stimulating adipocyte lipolysis (21, 30), alleviating insulin resistance and glucose homeostasis (10, 31, 33), or attenuating systemic inflammation (56, 57), in a complementary or synergistic manner probably mediated through concurrent targeting of metabolic/inflammatory signaling pathways including CPT-Ia (20, 21), PDHC (8, 19), PPAR- (21, 31, 37), AMPK (30, 37), or NF-B (31, 34)

Vitamin C is an antioxidant that helps brighten the skin through what is called tyrosinase inhibitors

(54) demonstrated that crocodilian oil exhibits significantly greater free radical scavenging activity than olive oil, particularly in detoxifying hydrogen peroxide

In all cases patients are presented with multiple caries, required extractions, or generalized tooth damage