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The diagnosis of type 2 diabetes mellitus (T2DM) was established based on either a fasting plasma glucose level 7.0 mmol/L, HbA1c 6.5%, or the current use of oral antidiabetic agents or insulin therapy

22,23 Obese HFpEF patients have greater LV hypertrophy and pulmonary capillary wedge pressure, increased LV filling pressures and severe right ventricular dysfunction compared with non-obese HFpEF patients

Current evidence Most research focuses on standard and maximum doses

[DOI] [PMC free article] [PubMed] [Google Scholar] Ji Z, Hadac EM, Henne RM, Patel SA, Lybrand TP, Miller LJ

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1 2 Perry T, Lahiri DK, Sambamurti K, Chen D, Mattson MP, Egan JM, Greig NH (June 2003)