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Ongoing monitoring of kidney function and overall health is critical to ensure the treatment remains both safe and effective

Falta de eficacia: Si despus de alcanzar la dosis de mantenimiento durante al menos 3 meses no observa mejora en el control glucmico (para diabetes) o prdida de peso significativa (para manejo de peso), debe discutir con su mdico si es apropiado aumentar la dosis, cambiar a un medicamento diferente o agregar terapias adicionales

E.NauckM.BaileyT.MontanyaE.CuddihyR.FilettiS.et al (2010)

Furthermore, GLP-1RAs exhibit antiproliferative effects on vascular smooth muscle cells and anti-inflammatory actions on macrophages, contributing to the prevention of atherosclerosis development and progression

Semaglutide may mediate glucose transport through AMPK/SIRT1 because GLP-1RA can activate SIRT1 through cAMP-dependent PKA, and GLUT4 is a downstream of SIRT1 [45]

Medical Disclaimer: This article is for educational purposes only and does not replace professional medical advice