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doi: 10.1080/08916930701574331

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Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling

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Three kinds of ligands can be identified: those which promote both desensitization and internalization ([Met 5 ]-enkephalin, etorphine, and methadone), those which induce a desensitization without internalization (morphine and oxymorphone) and oxycodone which promote neither desensitization nor internalization