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In addition, high AIB1 expression has been associated with a better outcome in the tamoxifen-untreated group, whereas it has been associated with worse prognosis in terms of free survival in the tamoxifen-treated patients when the AIB1 levels were compared between tamoxifen untreated- and treated patients (Osborne et al ., 2003)

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However, this study evaluated the effect of NAC given as a single dose of 21 g (approximately 300 mg/Kg) for 20 h