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They also provide minimal nutrition when your appetite is already reduced

But life is difficult, he said

In the multiple ascending dose groups, weight loss persisted for up to 150 days after the final dose [8]

That rules out both weight and glucose as the primary explanation

GLP-1 medications cause some patients to eat less than 1,200 calories per day during titration

Tropifexor, a farnesoid X receptor agonist for the treatment of non-alcoholic steatohepatitis: interim results based on baseline body mass index from first two parts of phase 2b study FLIGHT-FXR [abstract]
