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Tuba Tunal Akbay: Conceptualization, Supervision, Writing Original Draft

We found that 2 weeks of glutathione supplementation did not affect plasma glutathione concentration in the basal state

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In this category, cis -6-(2-acetylvinylthio)-purine (cAVTP) and trans -6-(2-acetylvinylthio)-guanine (tAVTG) contain active thiopurines (6-mercaptopurine and 6-thioguanine, respectively) liberated intracellularly after GSH-conjugation catalyzed by GST M1-1, M2-2, and A4-4, but not GST P1-1 ( Figure 2B )

This process is emerging as a key mechanism in airway inflammation and pathogenesis of bronchiectasis

Surprisingly, in type 2 diabetes, genes positively correlated with exocytosis were upregulated whereas those negatively correlated were downregulated, possibly reflecting compensatory adaptation to increased insulin demand