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Personalized Medicine: The Precision Peptide Genetic Test Advantage Not all patients respond equally to GLP-1 therapy

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doi: 10.2337/dbi18-0045

25 Ala substitutions in positions 10 and 11 of GIP had little negative effect on insulinotropic activity while position 12 and 14 mutations had a greater negative effect

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Together, these mechanisms not only promote weight loss but also help improve overall metabolic health
