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The variable results stem from multiple factors: inconsistent sublingual absorption between individuals, differences in formulation quality between compounding pharmacies, variations in user technique, concurrent lifestyle changes that may contribute to weight loss independently, and the well-documented placebo effect in weight loss interventions

doi: 10.3389/fphar.2026.1798309 Received 28 January 2026 Revised 27 February 2026 Accepted 28 February 2026 Published 26 March 2026 Volume 17 - 2026 Edited by Marcos Roberto De Oliveira, Federal University of Rio Grande do Sul, Brazil Reviewed by Maria Jos De Rosa, CONICET Baha Blanca, Argentina Shubham Teli, BVVS Hanagal Shri Kumareshwar College of Pharmacy, India Updates Copyright 2026 Juthi, Ansari, Ahmed, Khan, Seidel, Kumar, Kumari, McKillop, Abdel-Wahab and Flatt

10.3389/fimmu.2014.00682 [DOI] [PMC free article] [PubMed] [Google Scholar] 9.Levitt DG, Levitt MD

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However, cannabis may influence appetite, digestion and eating behaviours, which could affect your treatment experience and make maintaining consistent weight-loss progress more challenging

If such symptoms occur while on treatment, immediate medical assistance is crucial to address potential complications