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The data suggests that Eli Lilly's GLP-1 drugs could be taking market share from Novo Nordisk

Incretin therapies that target gastric inhibitory polypeptide (GIP) or glucagon-like peptide-1 (GLP-1) offer new ways to manage blood glucose levels, body weight, and lipid metabolism

[DOI] [PubMed] [Google Scholar] 56.Alicic R

The rates are remarkably similar across all three, despite their different mechanisms: Semaglutide: Nausea approximately 18%, diarrhea approximately 12%, vomiting approximately 8% Tirzepatide: Nausea 17-22% (dose dependent), diarrhea 13-16%, vomiting 6-10% Retatrutide: Nausea 16-25% (dose dependent), diarrhea 15-22%, vomiting 8-13% The pattern holds consistently

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Clinical trials studying semaglutide in people with chronic kidney disease and type 2 diabetes showed a reduction in kidney disease progression and kidney-related death